Vomiting after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

3,844 reports to the FDA describe vomiting in dogs given Febantel + Praziquantel + Pyrantel. That is 57% of all reports for this medicine, compared with 28% across reports for all dog medicines, so it is reported unusually often with this medicine.

3,844Reports

40%Marked serious

67%Recovered

2.1%Died or euthanised

Same dayTypical onset

How soon it started

Same day

2,621 82%

1–2 days

305 9.6%

3–7 days

74 2.3%

1–4 weeks

98 3.1%

Over a month

92 2.9%

How the animals did

Recovered

2,550 66%

Recovered with lasting effects

7 0.2%

Still unwell when reported

146 3.8%

Died

61 1.6%

Euthanised

20 0.5%

Not known

1,060 28%

Problems reported at the same time

433 11%

368 9.6%

307 8.0%

146 3.8%

136 3.5%

135 3.5%

89 2.3%

83 2.2%

Age of the animals

Under 1 year

1,659

1–3 years

889

4–7 years

524

8–11 years

323

12+ years

163

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause vomiting in dogs?: 3,844 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

Vomiting after Pyrantel + Sarolaner (Simparica Trio) 10,822 reports · 20% of its reports
Vomiting after Fenbendazole 2,054 reports · 35% of its reports
Vomiting after Pyrantel 1,528 reports · 32% of its reports
Vomiting after Praziquantel + Pyrantel 1,813 reports · 49% of its reports
Vomiting after Praziquantel 255 reports · 23% of its reports

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with vomiting