Vomiting after Praziquantel + Pyrantel in dogs

1,813 reports to the FDA describe vomiting in dogs given Praziquantel + Pyrantel. That is 49% of all reports for this medicine, compared with 28% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,813Reports

23%Marked serious

42%Recovered

6.5%Died or euthanised

Same dayTypical onset

How soon it started

Same day

1,021 69%

1–2 days

287 19%

3–7 days

79 5.4%

1–4 weeks

37 2.5%

Over a month

49 3.3%

How the animals did

Recovered

754 42%

Recovered with lasting effects

5 0.3%

Still unwell when reported

44 2.4%

Died

104 5.7%

Euthanised

14 0.8%

Not known

892 49%

Problems reported at the same time

472 26%

387 21%

352 19%

109 6.0%

82 4.5%

71 3.9%

69 3.8%

65 3.6%

Age of the animals

Under 1 year

754

1–3 years

500

4–7 years

249

8–11 years

140

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause vomiting in dogs?: 1,813 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

Vomiting after Pyrantel + Sarolaner (Simparica Trio) 10,822 reports · 20% of its reports
Vomiting after Febantel + Praziquantel + Pyrantel (Drontal Plus) 3,844 reports · 57% of its reports
Vomiting after Fenbendazole 2,054 reports · 35% of its reports
Vomiting after Pyrantel 1,528 reports · 32% of its reports
Vomiting after Praziquantel 255 reports · 23% of its reports

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with vomiting