Loss of appetite after Praziquantel + Pyrantel in dogs

626 reports to the FDA describe loss of appetite in dogs given Praziquantel + Pyrantel. That is 17% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

626Reports
53%Marked serious
22%Recovered
15%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
206 40%
1–2 days
227 45%
3–7 days
58 11%
1–4 weeks
12 2.4%
Over a month
6 1.2%

How the animals did

Recovered
136 22%
Recovered with lasting effects
4 0.6%
Still unwell when reported
25 4.0%
Died
79 13%
Euthanised
15 2.4%
Not known
367 59%

Problems reported at the same time

352 56%
348 56%
244 39%
89 14%
38 6.1%

Age of the animals

Under 1 year
306
1–3 years
117
4–7 years
85
8–11 years
59
12+ years
37

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause loss of appetite in dogs?
626 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with loss of appetite