Loss of appetite after Pyrantel + Sarolaner (Simparica Trio) in dogs

2,726 reports to the FDA describe loss of appetite in dogs given Pyrantel + Sarolaner. That is 5.1% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

Sponsored

How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Pyrantel treats roundworms and hookworms. Sarolaner kills fleas, ticks and some mites; monthly.

Products with this combination include Simparica Trio (which also contains moxidectin). The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Pyrantel + Sarolaner cause loss of appetite in dogs?

2,726 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 1 day of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

• Loss of appetite after Febantel + Praziquantel + Pyrantel (Drontal Plus) 577 reports · 8.6% of its reports
• Loss of appetite after Fenbendazole 981 reports · 17% of its reports
• Loss of appetite after Pyrantel 621 reports · 13% of its reports
• Loss of appetite after Praziquantel + Pyrantel 626 reports · 17% of its reports
• Loss of appetite after Praziquantel 118 reports · 11% of its reports

All reported side effects of Pyrantel + Sarolaner in dogs · Medicines most reported with loss of appetite