Breathing problems after Praziquantel + Pyrantel in dogs

175 reports to the FDA describe breathing problems in dogs given Praziquantel + Pyrantel. That is 4.7% of all reports for this medicine, compared with 2.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

175Reports
67%Marked serious
29%Recovered
13%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
115 73%
1–2 days
28 18%
3–7 days
10 6.3%
1–4 weeks
1 0.6%
Over a month
4 2.5%

How the animals did

Recovered
49 28%
Recovered with lasting effects
1 0.6%
Still unwell when reported
5 2.9%
Died
19 11%
Euthanised
4 2.3%
Not known
97 55%

Problems reported at the same time

Age of the animals

Under 1 year
42
1–3 years
52
4–7 years
37
8–11 years
20
12+ years
16

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause breathing problems in dogs?
175 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Breathing problems with similar medicines

All reported side effects of Praziquantel + Pyrantel in dogs · Medicines most reported with breathing problems