Breathing problems after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

126 reports to the FDA describe breathing problems in dogs given Febantel + Praziquantel + Pyrantel. That is 1.9% of all reports for this medicine, compared with 2.7% across reports for all dog medicines.

126Reports
46%Marked serious
38%Recovered
11%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
67 61%
1–2 days
15 14%
3–7 days
12 11%
1–4 weeks
10 9.2%
Over a month
5 4.6%

How the animals did

Recovered
47 37%
Recovered with lasting effects
1 0.8%
Still unwell when reported
19 15%
Died
14 11%
Not known
45 36%

Problems reported at the same time

Age of the animals

Under 1 year
39
1–3 years
32
4–7 years
17
8–11 years
20
12+ years
15

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause breathing problems in dogs?
126 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Breathing problems with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with breathing problems