Death after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

214 reports to the FDA describe death in dogs given Febantel + Praziquantel + Pyrantel. That is 3.2% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported less often than average with this medicine.

214Reports
75%Marked serious
0.0%Recovered
99%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
53 39%
1–2 days
39 28%
3–7 days
14 10%
1–4 weeks
18 13%
Over a month
13 9.5%

How the animals did

Died
168 79%
Euthanised
44 21%
Not known
2 0.9%

Problems reported at the same time

Age of the animals

Under 1 year
97
1–3 years
22
4–7 years
25
8–11 years
28
12+ years
17

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause death in dogs?
214 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with death