Death after Pyrantel in dogs

The FDA has received 693 reports of death in dogs after Pyrantel. That is 14% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

693Reports

47%Marked serious

0.0%Recovered

99%Died or euthanised

2 daysTypical onset

How soon it started

Same day

90 32%

1–2 days

67 24%

3–7 days

36 13%

1–4 weeks

57 20%

Over a month

32 11%

How the animals did

Still unwell when reported

1 0.1%

Died

610 88%

Euthanised

76 11%

Not known

6 0.9%

Problems reported at the same time

211 30%

209 30%

176 25%

170 25%

70 10%

63 9.1%

60 8.7%

51 7.4%

Age of the animals

Under 1 year

478

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause death in dogs?: 693 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Pyrantel + Sarolaner (Simparica Trio) 896 reports · 1.7% of its reports
Death after Febantel + Praziquantel + Pyrantel (Drontal Plus) 214 reports · 3.2% of its reports
Death after Fenbendazole 512 reports · 8.7% of its reports
Death after Praziquantel + Pyrantel 244 reports · 6.6% of its reports
Death after Praziquantel 50 reports · 4.5% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with death