Seizures after Pyrantel in dogs

The FDA has received 229 reports of seizures in dogs after Pyrantel. That is 4.8% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

229Reports

59%Marked serious

14%Recovered

32%Died or euthanised

1 daysTypical onset

How soon it started

Same day

52 38%

1–2 days

34 25%

3–7 days

15 11%

1–4 weeks

22 16%

Over a month

14 10%

How the animals did

Recovered

32 14%

Recovered with lasting effects

1 0.4%

Still unwell when reported

44 19%

Died

57 25%

Euthanised

16 7.0%

Not known

79 34%

Problems reported at the same time

70 31%

49 21%

38 17%

37 16%

36 16%

32 14%

21 9.2%

21 9.2%

Age of the animals

Under 1 year

124

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause seizures in dogs?: 229 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Pyrantel + Sarolaner (Simparica Trio) 4,687 reports · 8.8% of its reports
Seizures after Febantel + Praziquantel + Pyrantel (Drontal Plus) 108 reports · 1.6% of its reports
Seizures after Fenbendazole 185 reports · 3.1% of its reports
Seizures after Praziquantel + Pyrantel 96 reports · 2.6% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with seizures