Liver problems after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs
The FDA has received 70 reports of liver problems in dogs after Febantel + Praziquantel + Pyrantel. That is 1.0% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported less often than average with this medicine.
70Reports
66%Marked serious
11%Recovered
33%Died or euthanised
3 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.
Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Febantel + Praziquantel + Pyrantel cause liver problems in dogs?
- 70 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 3 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Liver problems with similar medicines
- Liver problems after Pyrantel + Sarolaner (Simparica Trio) 695 reports · 1.3% of its reports
- Liver problems after Fenbendazole 140 reports · 2.4% of its reports
- Liver problems after Pyrantel 126 reports · 2.6% of its reports
- Liver problems after Praziquantel + Pyrantel 31 reports · 0.8% of its reports
All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with liver problems