Diarrhea after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

815 reports to the FDA describe diarrhea in dogs given Febantel + Praziquantel + Pyrantel. That is 12% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

815Reports

46%Marked serious

25%Recovered

6.0%Died or euthanised

1 daysTypical onset

How soon it started

Same day

277 43%

1–2 days

149 23%

3–7 days

67 10%

1–4 weeks

88 14%

Over a month

58 9.1%

How the animals did

Recovered

202 25%

Recovered with lasting effects

2 0.2%

Still unwell when reported

97 12%

Died

34 4.2%

Euthanised

15 1.8%

Not known

465 57%

Problems reported at the same time

433 53%

174 21%

154 19%

126 15%

Didn't work as expected

72 8.8%

Death

48 5.9%

Behaviour change

42 5.2%

Overdose

41 5.0%

Age of the animals

Under 1 year

408

1–3 years

153

4–7 years

107

8–11 years

12+ years

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause diarrhea in dogs?: 815 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

Diarrhea after Pyrantel + Sarolaner (Simparica Trio) 4,331 reports · 8.1% of its reports
Diarrhea after Fenbendazole 1,091 reports · 19% of its reports
Diarrhea after Pyrantel 785 reports · 16% of its reports
Diarrhea after Praziquantel + Pyrantel 740 reports · 20% of its reports
Diarrhea after Praziquantel 139 reports · 13% of its reports

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with diarrhea