Tremors after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

149 reports to the FDA describe tremors in dogs given Febantel + Praziquantel + Pyrantel. That is 2.2% of all reports for this medicine, compared with 3.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

149Reports
45%Marked serious
34%Recovered
6.0%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
64 55%
1–2 days
24 21%
3–7 days
5 4.3%
1–4 weeks
12 10%
Over a month
12 10%

How the animals did

Recovered
49 33%
Recovered with lasting effects
2 1.3%
Still unwell when reported
17 11%
Died
6 4.0%
Euthanised
3 2.0%
Not known
72 48%

Problems reported at the same time

Age of the animals

Under 1 year
54
1–3 years
35
4–7 years
38
8–11 years
11
12+ years
9

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause tremors in dogs?
149 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with tremors