Liver problems after Prednisolone + Trimeprazine in dogs
247 reports to the FDA describe liver problems in dogs given Prednisolone + Trimeprazine. That is 12% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.
247Reports
32%Marked serious
7.3%Recovered
20%Died or euthanised
18 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Prednisolone reduces inflammation and immune activity.
Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.
Questions owners ask
- Can Prednisolone + Trimeprazine cause liver problems in dogs?
- 247 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 18 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Liver problems with similar medicines
- Liver problems after Prednisone 1,077 reports · 12% of its reports
- Liver problems after Dexamethasone 500 reports · 18% of its reports
- Liver problems after Prednisolone 165 reports · 14% of its reports
- Liver problems after Miconazole + Polymyxin B + Prednisolone 25 reports · 2.3% of its reports
- Liver problems after Dexamethasone + Neomycin + Thiabendazole 32 reports · 5.0% of its reports
- Liver problems after Dexamethasone + Neomycin + Polymyxin B 20 reports · 12% of its reports
All reported side effects of Prednisolone + Trimeprazine in dogs · Medicines most reported with liver problems