Loss of appetite after Prednisolone + Trimeprazine in dogs

253 reports to the FDA describe loss of appetite in dogs given Prednisolone + Trimeprazine. That is 12% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

253Reports
40%Marked serious
18%Recovered
24%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
32 21%
1–2 days
21 14%
3–7 days
22 14%
1–4 weeks
37 24%
Over a month
40 26%

How the animals did

Recovered
42 17%
Recovered with lasting effects
4 1.6%
Still unwell when reported
92 36%
Died
30 12%
Euthanised
30 12%
Not known
55 22%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
44
4–7 years
77
8–11 years
77
12+ years
39

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone + Trimeprazine cause loss of appetite in dogs?
253 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Prednisolone + Trimeprazine in dogs · Medicines most reported with loss of appetite