Recumbency after Polysulfated Glycosaminoglycan in dogs

The FDA has received 74 reports of recumbency in dogs after Polysulfated Glycosaminoglycan. That is 1.4% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

74Reports
51%Marked serious
15%Recovered
42%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
12 33%
1–2 days
6 17%
3–7 days
5 14%
1–4 weeks
5 14%
Over a month
8 22%

How the animals did

Recovered
11 15%
Still unwell when reported
13 18%
Died
20 27%
Euthanised
11 15%
Not known
19 26%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
6
8–11 years
31
12+ years
34

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause recumbency in dogs?
74 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Recumbency with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with recumbency