Recumbency after Melarsomine (Immiticide) in dogs

The FDA has received 261 reports of recumbency in dogs after Melarsomine. That is 1.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

261Reports

25%Marked serious

5.7%Recovered

19%Died or euthanised

6 daysTypical onset

How soon it started

Same day

21 30%

1–2 days

5 7.2%

3–7 days

10 14%

1–4 weeks

12 17%

Over a month

21 30%

How the animals did

Recovered

15 5.7%

Still unwell when reported

25 9.6%

Died

44 17%

Euthanised

6 2.3%

Not known

171 66%

Problems reported at the same time

72 28%

56 21%

46 18%

46 18%

45 17%

42 16%

39 15%

35 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

104

8–11 years

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause recumbency in dogs?: 261 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Recumbency with similar medicines

Recumbency after Polysulfated Glycosaminoglycan 74 reports · 1.4% of its reports
Recumbency after Diphenhydramine 46 reports · 1.0% of its reports
Recumbency after Butorphanol 44 reports · 1.0% of its reports
Recumbency after Cefpodoxime 29 reports · 0.7% of its reports
Recumbency after Tramadol 29 reports · 0.8% of its reports
Recumbency after Desoxycorticosterone Pivalate 24 reports · 0.7% of its reports
Recumbency after Propofol 20 reports · 0.7% of its reports
Recumbency after Dirlotapide 20 reports · 0.7% of its reports
Recumbency after Atipamezole 24 reports · 0.9% of its reports
Recumbency after Famotidine 25 reports · 0.9% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with recumbency