Malaise after Polysulfated Glycosaminoglycan in dogs

55 reports to the FDA describe malaise in dogs given Polysulfated Glycosaminoglycan. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports
62%Marked serious
18%Recovered
22%Died or euthanised
48 daysTypical onset
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How soon it started

Same day
5 19%
1–2 days
2 7.7%
3–7 days
2 7.7%
1–4 weeks
4 15%
Over a month
13 50%

How the animals did

Recovered
10 18%
Still unwell when reported
19 35%
Died
5 9.1%
Euthanised
7 13%
Not known
14 25%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
4
4–7 years
6
8–11 years
24
12+ years
18

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause malaise in dogs?
55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 48 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with malaise