Malaise after Desoxycorticosterone Pivalate in dogs

The FDA has received 92 reports of malaise in dogs after Desoxycorticosterone Pivalate. That is 2.8% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

92Reports
70%Marked serious
17%Recovered
11%Died or euthanised
31 daysTypical onset
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How soon it started

Same day
6 14%
1–2 days
4 9.3%
3–7 days
0 0.0%
1–4 weeks
11 26%
Over a month
22 51%

How the animals did

Recovered
14 15%
Recovered with lasting effects
2 2.2%
Still unwell when reported
30 33%
Died
3 3.3%
Euthanised
7 7.6%
Not known
36 39%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
11
4–7 years
26
8–11 years
34
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause malaise in dogs?
92 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 31 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with malaise