Malaise after Tramadol in dogs

The FDA has received 48 reports of malaise in dogs after Tramadol. That is 1.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

48Reports
73%Marked serious
19%Recovered
42%Died or euthanised
42 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
4 15%
3–7 days
6 22%
1–4 weeks
2 7.4%
Over a month
15 56%

How the animals did

Recovered
8 17%
Recovered with lasting effects
1 2.1%
Still unwell when reported
14 29%
Died
5 10%
Euthanised
15 31%
Not known
5 10%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
3
4–7 years
13
8–11 years
18
12+ years
12

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause malaise in dogs?
48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 42 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

All reported side effects of Tramadol in dogs · Medicines most reported with malaise