Pain after Polysulfated Glycosaminoglycan in dogs

The FDA has received 157 reports of pain in dogs after Polysulfated Glycosaminoglycan. That is 2.9% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

157Reports
47%Marked serious
13%Recovered
23%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
24 27%
1–2 days
14 16%
3–7 days
5 5.7%
1–4 weeks
13 15%
Over a month
32 36%

How the animals did

Recovered
20 13%
Still unwell when reported
39 25%
Died
12 7.6%
Euthanised
24 15%
Not known
62 39%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
6
4–7 years
26
8–11 years
65
12+ years
50

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause pain in dogs?
157 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pain with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with pain