Vocalising after Polysulfated Glycosaminoglycan in dogs

The FDA has received 97 reports of vocalising in dogs after Polysulfated Glycosaminoglycan. That is 1.8% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

97Reports
38%Marked serious
20%Recovered
25%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
16 25%
1–2 days
8 12%
3–7 days
6 9.2%
1–4 weeks
15 23%
Over a month
20 31%

How the animals did

Recovered
19 20%
Still unwell when reported
14 14%
Died
11 11%
Euthanised
13 13%
Not known
40 41%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
4
4–7 years
15
8–11 years
35
12+ years
35

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause vocalising in dogs?
97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with vocalising