Vocalising after Melarsomine (Immiticide) in dogs

The FDA has received 548 reports of vocalising in dogs after Melarsomine. That is 2.4% of all reports for this medicine, compared with 1.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

548Reports
44%Marked serious
10%Recovered
8.9%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
201 58%
1–2 days
29 8.4%
3–7 days
13 3.8%
1–4 weeks
31 9.0%
Over a month
70 20%

How the animals did

Recovered
56 10%
Recovered with lasting effects
1 0.2%
Still unwell when reported
136 25%
Died
38 6.9%
Euthanised
11 2.0%
Not known
306 56%

Problems reported at the same time

Age of the animals

Under 1 year
12
1–3 years
295
4–7 years
159
8–11 years
50
12+ years
7

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause vocalising in dogs?
548 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vocalising with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with vocalising