Behaviour change after Polysulfated Glycosaminoglycan in dogs

178 reports to the FDA describe behaviour change in dogs given Polysulfated Glycosaminoglycan. That is 3.3% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

178Reports
46%Marked serious
31%Recovered
12%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
33 27%
1–2 days
11 8.9%
3–7 days
14 11%
1–4 weeks
24 20%
Over a month
41 33%

How the animals did

Recovered
54 30%
Recovered with lasting effects
1 0.6%
Still unwell when reported
41 23%
Died
11 6.2%
Euthanised
11 6.2%
Not known
60 34%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
30
8–11 years
72
12+ years
62

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause behaviour change in dogs?
178 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with behaviour change