Behaviour change after Cefpodoxime in dogs

The FDA has received 162 reports of behaviour change in dogs after Cefpodoxime. That is 4.0% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

162Reports
36%Marked serious
28%Recovered
9.9%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
31 22%
1–2 days
25 18%
3–7 days
22 16%
1–4 weeks
29 21%
Over a month
34 24%

How the animals did

Recovered
46 28%
Still unwell when reported
63 39%
Died
5 3.1%
Euthanised
11 6.8%
Not known
37 23%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
40
4–7 years
49
8–11 years
46
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause behaviour change in dogs?
162 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Cefpodoxime in dogs · Medicines most reported with behaviour change