Behaviour change after Isoflurane in dogs

The FDA has received 96 reports of behaviour change in dogs after Isoflurane. That is 3.5% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

96Reports
59%Marked serious
34%Recovered
20%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
35 45%
1–2 days
15 19%
3–7 days
11 14%
1–4 weeks
5 6.4%
Over a month
12 15%

How the animals did

Recovered
31 32%
Recovered with lasting effects
2 2.1%
Still unwell when reported
24 25%
Died
14 15%
Euthanised
5 5.2%
Not known
20 21%

Problems reported at the same time

Age of the animals

Under 1 year
15
1–3 years
25
4–7 years
25
8–11 years
19
12+ years
8

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause behaviour change in dogs?
96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with behaviour change