Reluctant to move after Phenylpropanolamine (Proin) in dogs

The FDA has received 28 reports of reluctant to move in dogs after Phenylpropanolamine. That is 0.7% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

28Reports

57%Marked serious

43%Recovered

14%Died or euthanised

1 daysTypical onset

How soon it started

Same day

9 47%

1–2 days

1 5.3%

3–7 days

1 5.3%

1–4 weeks

2 11%

Over a month

6 32%

How the animals did

Recovered

12 43%

Still unwell when reported

6 21%

Died

1 3.6%

Euthanised

3 11%

Not known

6 21%

Problems reported at the same time

11 39%

10 36%

8 29%

7 25%

Restlessness or agitation

4 14%

Vocalising

4 14%

Death

4 14%

Anxiety

3 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause reluctant to move in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reluctant to move with similar medicines

Reluctant to move after Trilostane (Vetoryl) 113 reports · 0.9% of its reports
Reluctant to move after Insulin 33 reports · 0.4% of its reports
Reluctant to move after Levothyroxine 22 reports · 0.7% of its reports

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with reluctant to move