Reluctant to move after Trilostane (Vetoryl) in dogs

The FDA has received 113 reports of reluctant to move in dogs after Trilostane. That is 0.9% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

113Reports
58%Marked serious
22%Recovered
13%Died or euthanised
31 daysTypical onset
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How soon it started

Same day
4 4.4%
1–2 days
12 13%
3–7 days
8 8.9%
1–4 weeks
21 23%
Over a month
45 50%

How the animals did

Recovered
24 21%
Recovered with lasting effects
1 0.9%
Still unwell when reported
20 18%
Died
3 2.7%
Euthanised
12 11%
Not known
53 47%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
11
8–11 years
51
12+ years
51

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause reluctant to move in dogs?
113 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 31 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reluctant to move with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with reluctant to move