Hyperkalaemia after Trilostane (Vetoryl) in dogs

1,751 reports to the FDA describe hyperkalaemia in dogs given Trilostane. That is 15% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause hyperkalaemia in dogs?

1,751 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 41 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperkalaemia with similar medicines

• Hyperkalaemia after Insulin 142 reports · 1.9% of its reports
• Hyperkalaemia after Phenylpropanolamine (Proin) 23 reports · 0.6% of its reports
• Hyperkalaemia after Levothyroxine 56 reports · 1.9% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with hyperkalaemia