Lethargy after Trilostane (Vetoryl) in dogs

The FDA has received 2,568 reports of lethargy in dogs after Trilostane. That is 22% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause lethargy in dogs?

2,568 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 28 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

• Lethargy after Insulin 895 reports · 12% of its reports
• Lethargy after Phenylpropanolamine (Proin) 668 reports · 16% of its reports
• Lethargy after Levothyroxine 470 reports · 16% of its reports

All reported side effects of Trilostane in dogs · Medicines most reported with lethargy