Weight loss after Trilostane (Vetoryl) in dogs

1,496 reports to the FDA describe weight loss in dogs given Trilostane. That is 13% of all reports for this medicine, compared with 1.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,496Reports
56%Marked serious
5.2%Recovered
15%Died or euthanised
61 daysTypical onset
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How soon it started

Same day
57 5.2%
1–2 days
32 2.9%
3–7 days
63 5.7%
1–4 weeks
232 21%
Over a month
712 65%

How the animals did

Recovered
73 4.9%
Recovered with lasting effects
5 0.3%
Still unwell when reported
256 17%
Died
50 3.3%
Euthanised
174 12%
Not known
938 63%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
132
8–11 years
721
12+ years
627

About this medicine

Trilostane treats Cushing's disease (an overactive adrenal gland).

Products with this ingredient include Vetoryl. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Trilostane cause weight loss in dogs?
1,496 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 61 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight loss with similar medicines

All reported side effects of Trilostane in dogs · Medicines most reported with weight loss