Loose stool after Phenylpropanolamine (Proin) in dogs

52 reports to the FDA describe loose stool in dogs given Phenylpropanolamine. That is 1.3% of all reports for this medicine, compared with 0.9% across reports for all dog medicines.

52Reports
31%Marked serious
33%Recovered
3.8%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
7 21%
1–2 days
12 35%
3–7 days
2 5.9%
1–4 weeks
4 12%
Over a month
9 26%

How the animals did

Recovered
17 33%
Still unwell when reported
15 29%
Died
1 1.9%
Euthanised
1 1.9%
Not known
18 35%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
12
8–11 years
19
12+ years
11

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause loose stool in dogs?
52 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loose stool with similar medicines

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with loose stool