Excessive thirst after Phenylpropanolamine (Proin) in dogs

180 reports to the FDA describe excessive thirst in dogs given Phenylpropanolamine. That is 4.3% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

180Reports
49%Marked serious
30%Recovered
10%Died or euthanised
1 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
45 40%
1–2 days
23 21%
3–7 days
8 7.1%
1–4 weeks
10 8.9%
Over a month
26 23%

How the animals did

Recovered
53 29%
Recovered with lasting effects
1 0.6%
Still unwell when reported
42 23%
Died
9 5.0%
Euthanised
9 5.0%
Not known
66 37%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
15
4–7 years
35
8–11 years
65
12+ years
61

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause excessive thirst in dogs?
180 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive thirst with similar medicines

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with excessive thirst