Lotilaner (Credelio) side effects in dogs
9,960 reports sent to the FDA between 2015 and 2026 involve Lotilaner in dogs. The most reported problems were vomiting, diarrhea, lethargy. 15% were marked serious, and where it was recorded, signs eased after stopping the medicine in 100% of cases.
About this medicine
Lotilaner kills fleas and ticks; monthly chewable.
Products with this ingredient include Credelio. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (7,767 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 736 reports
- Golden Retriever 376 reports
- German Shepherd Dog 277 reports
- Australian Shepherd Dog 264 reports
- Shih Tzu 206 reports
- Chihuahua 202 reports
- Yorkshire Terrier 193 reports
- Pit Bull 141 reports
- French Bulldog 139 reports
- Boxer (german Boxer) 131 reports