Fluralaner (Bravecto) side effects in dogs

68,765 reports sent to the FDA between 2012 and 2026 involve Fluralaner in dogs. The most reported problems were vomiting, lethargy, diarrhea. 57% were marked serious, and where it was recorded, signs eased after stopping the medicine in 66% of cases.

68,765Reports
57%Marked serious
87%Only medicine involved
39%Recovered
3.2%Died or euthanised
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About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Most reported side effects

26,091 38%
6,278 9.1%
5,046 7.3%
3,501 5.1%
2,940 4.3%
2,377 3.5%
1,685 2.5%
897 1.3%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

How soon problems started

Same day
18,863 50%
1–2 days
4,687 12%
3–7 days
2,176 5.8%
1–4 weeks
3,208 8.5%
Over a month
8,782 23%

Time from the first dose to the first sign, where both dates were reported (37,716 reports).

How the animals did

Recovered
26,468 38%
Recovered with lasting effects
543 0.8%
Still unwell when reported
32,176 47%
Died
1,061 1.5%
Euthanised
1,144 1.7%
Not known
7,373 11%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other isoxazoline flea and tick medicines for dogs