Seizures after Fluralaner (Bravecto) in dogs

3,501 reports to the FDA describe seizures in dogs given Fluralaner. That is 5.1% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

3,501Reports
98%Marked serious
37%Recovered
16%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
384 21%
1–2 days
408 22%
3–7 days
224 12%
1–4 weeks
314 17%
Over a month
496 27%

How the animals did

Recovered
1,227 35%
Recovered with lasting effects
85 2.4%
Still unwell when reported
1,161 33%
Died
229 6.5%
Euthanised
339 9.7%
Not known
460 13%

Problems reported at the same time

Age of the animals

Under 1 year
157
1–3 years
895
4–7 years
1,039
8–11 years
780
12+ years
480

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause seizures in dogs?
3,501 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with seizures