Loss of appetite after Fluralaner (Bravecto) in dogs

4,987 reports to the FDA describe loss of appetite in dogs given Fluralaner. That is 7.3% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

4,987Reports

76%Marked serious

26%Recovered

14%Died or euthanised

1 daysTypical onset

How soon it started

Same day

1,183 34%

1–2 days

1,173 33%

3–7 days

376 11%

1–4 weeks

261 7.4%

Over a month

534 15%

How the animals did

Recovered

1,207 24%

Recovered with lasting effects

86 1.7%

Still unwell when reported

2,358 47%

Died

260 5.2%

Euthanised

461 9.2%

Not known

615 12%

Problems reported at the same time

2,863 57%

2,383 48%

1,482 30%

716 14%

668 13%

540 11%

473 9.5%

429 8.6%

Age of the animals

Under 1 year

453

1–3 years

1,258

4–7 years

1,333

8–11 years

1,217

12+ years

638

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause loss of appetite in dogs?: 4,987 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

Loss of appetite after Afoxolaner (NexGard) 4,773 reports · 8.4% of its reports
Loss of appetite after Sarolaner (Simparica) 1,442 reports · 8.7% of its reports
Loss of appetite after Lotilaner (Credelio) 791 reports · 7.9% of its reports
Loss of appetite after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 505 reports · 5.5% of its reports
Loss of appetite after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 302 reports · 9.8% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with loss of appetite