Not drinking after Fluralaner (Bravecto) in dogs

The FDA has received 487 reports of not drinking in dogs after Fluralaner. That is 0.7% of all reports for this medicine, compared with 0.5% across reports for all dog medicines.

487Reports

78%Marked serious

23%Recovered

19%Died or euthanised

1 daysTypical onset

How soon it started

Same day

115 35%

1–2 days

110 33%

3–7 days

39 12%

1–4 weeks

23 7.0%

Over a month

42 13%

How the animals did

Recovered

107 22%

Recovered with lasting effects

5 1.0%

Still unwell when reported

231 47%

Died

33 6.8%

Euthanised

60 12%

Not known

51 10%

Problems reported at the same time

429 88%

322 66%

221 45%

139 29%

99 20%

92 19%

64 13%

62 13%

Age of the animals

Under 1 year

1–3 years

140

4–7 years

123

8–11 years

102

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause not drinking in dogs?: 487 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not drinking with similar medicines

Not drinking after Afoxolaner (NexGard) 382 reports · 0.7% of its reports
Not drinking after Sarolaner (Simparica) 113 reports · 0.7% of its reports
Not drinking after Lotilaner (Credelio) 118 reports · 1.2% of its reports
Not drinking after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 52 reports · 0.6% of its reports
Not drinking after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 33 reports · 1.1% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with not drinking