Kidney problems after Fluralaner (Bravecto) in dogs

The FDA has received 896 reports of kidney problems in dogs after Fluralaner. That is 1.3% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

896Reports
93%Marked serious
8.4%Recovered
42%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
122 22%
1–2 days
140 25%
3–7 days
74 13%
1–4 weeks
65 12%
Over a month
156 28%

How the animals did

Recovered
39 4.4%
Recovered with lasting effects
36 4.0%
Still unwell when reported
340 38%
Died
130 15%
Euthanised
243 27%
Not known
108 12%

Problems reported at the same time

Age of the animals

Under 1 year
32
1–3 years
131
4–7 years
232
8–11 years
245
12+ years
237

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause kidney problems in dogs?
896 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with kidney problems