Liver problems after Sulfadimethoxine in dogs

51 reports to the FDA describe liver problems in dogs given Sulfadimethoxine. That is 5.5% of all reports for this medicine, compared with 4.6% across reports for all dog medicines.

51Reports
33%Marked serious
7.8%Recovered
27%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
5 23%
3–7 days
9 41%
1–4 weeks
5 23%
Over a month
3 14%

How the animals did

Recovered
4 7.8%
Still unwell when reported
12 24%
Died
8 16%
Euthanised
6 12%
Not known
21 41%

Problems reported at the same time

23 45%
19 37%
16 31%
14 27%
Hyperphosphataemia
12 24%

Age of the animals

Under 1 year
27
1–3 years
5
4–7 years
11
8–11 years
3
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Sulfadimethoxine cause liver problems in dogs?
51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Sulfadimethoxine in dogs · Medicines most reported with liver problems