Lethargy after Sulfadimethoxine in dogs

The FDA has received 172 reports of lethargy in dogs after Sulfadimethoxine. That is 19% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

172Reports
29%Marked serious
19%Recovered
23%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
13 15%
1–2 days
21 24%
3–7 days
15 17%
1–4 weeks
22 26%
Over a month
15 17%

How the animals did

Recovered
29 17%
Recovered with lasting effects
3 1.7%
Still unwell when reported
38 22%
Died
33 19%
Euthanised
6 3.5%
Not known
63 37%

Problems reported at the same time

Age of the animals

Under 1 year
126
1–3 years
22
4–7 years
12
8–11 years
5
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Sulfadimethoxine cause lethargy in dogs?
172 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Sulfadimethoxine in dogs · Medicines most reported with lethargy