Death after Sulfadimethoxine in dogs

The FDA has received 129 reports of death in dogs after Sulfadimethoxine. That is 14% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

129Reports
36%Marked serious
0.0%Recovered
99%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
7 18%
1–2 days
2 5.0%
3–7 days
10 25%
1–4 weeks
14 35%
Over a month
7 18%

How the animals did

Died
110 85%
Euthanised
18 14%
Not known
1 0.8%

Problems reported at the same time

Age of the animals

Under 1 year
97
1–3 years
4
4–7 years
9
8–11 years
5
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Sulfadimethoxine cause death in dogs?
129 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Sulfadimethoxine in dogs · Medicines most reported with death