Not drinking after Selamectin (Revolution) in dogs

42 reports to the FDA describe not drinking in dogs given Selamectin. That is 0.1% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported less often than average with this medicine.

42Reports

43%Marked serious

33%Recovered

21%Died or euthanised

1 daysTypical onset

How soon it started

Same day

19 49%

1–2 days

9 23%

3–7 days

4 10%

1–4 weeks

5 13%

Over a month

2 5.1%

How the animals did

Recovered

14 33%

Still unwell when reported

13 31%

Died

8 19%

Euthanised

1 2.4%

Not known

6 14%

Problems reported at the same time

38 90%

25 60%

15 36%

9 21%

9 21%

8 19%

7 17%

6 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause not drinking in dogs?: 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not drinking with similar medicines

Not drinking after Ivermectin + Pyrantel (Heartgard Plus) 282 reports · 0.2% of its reports
Not drinking after Milbemycin Oxime + Spinosad (Trifexis) 962 reports · 0.7% of its reports
Not drinking after Moxidectin (ProHeart 6) 169 reports · 0.3% of its reports
Not drinking after Milbemycin Oxime + Praziquantel (Interceptor Plus) 187 reports · 0.6% of its reports
Not drinking after Milbemycin Oxime (Interceptor) 43 reports · 0.1% of its reports
Not drinking after Ivermectin (Heartgard) 48 reports · 0.4% of its reports
Not drinking after Ivermectin + Praziquantel + Pyrantel (Iverhart Max) 41 reports · 0.5% of its reports

All reported side effects of Selamectin in dogs · Medicines most reported with not drinking