Loose stool after Pyrantel + Sarolaner (Simparica Trio) in dogs
The FDA has received 329 reports of loose stool in dogs after Pyrantel + Sarolaner. That is 0.6% of all reports for this medicine, compared with 0.9% across reports for all dog medicines.
329Reports
39%Marked serious
33%Recovered
3.6%Died or euthanised
Same dayTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Pyrantel treats roundworms and hookworms. Sarolaner kills fleas, ticks and some mites; monthly.
Products with this combination include Simparica Trio (which also contains moxidectin). The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Pyrantel + Sarolaner cause loose stool in dogs?
- 329 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Loose stool with similar medicines
- Loose stool after Febantel + Praziquantel + Pyrantel (Drontal Plus) 145 reports · 2.2% of its reports
- Loose stool after Fenbendazole 131 reports · 2.2% of its reports
- Loose stool after Pyrantel 84 reports · 1.8% of its reports
- Loose stool after Praziquantel + Pyrantel 146 reports · 4.0% of its reports
All reported side effects of Pyrantel + Sarolaner in dogs · Medicines most reported with loose stool