Loose stool after Pyrantel in dogs

84 reports to the FDA describe loose stool in dogs given Pyrantel. That is 1.8% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

84Reports

30%Marked serious

13%Recovered

15%Died or euthanised

1 daysTypical onset

How soon it started

Same day

13 34%

1–2 days

11 29%

3–7 days

1 2.6%

1–4 weeks

8 21%

Over a month

5 13%

How the animals did

Recovered

10 12%

Recovered with lasting effects

1 1.2%

Still unwell when reported

16 19%

Died

12 14%

Euthanised

1 1.2%

Not known

44 52%

Problems reported at the same time

33 39%

29 35%

25 30%

18 21%

13 15%

13 15%

Didn't work as expected

13 15%

Liver problems

9 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause loose stool in dogs?: 84 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loose stool with similar medicines

Loose stool after Pyrantel + Sarolaner (Simparica Trio) 329 reports · 0.6% of its reports
Loose stool after Febantel + Praziquantel + Pyrantel (Drontal Plus) 145 reports · 2.2% of its reports
Loose stool after Fenbendazole 131 reports · 2.2% of its reports
Loose stool after Praziquantel + Pyrantel 146 reports · 4.0% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with loose stool