Prednisone side effects in dogs

8,940 reports sent to the FDA between 1996 and 2026 involve Prednisone in dogs. The most reported problems were vomiting, loss of appetite, lethargy. 52% were marked serious, and where it was recorded, signs eased after stopping the medicine in 25% of cases.

8,940Reports
52%Marked serious
0.2%Only medicine involved
24%Recovered
13%Died or euthanised
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About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop ticks
14 0.2%
Didn't stop mites
4 0.0%

How soon problems started

Same day
1,224 19%
1–2 days
676 10%
3–7 days
594 9.0%
1–4 weeks
1,380 21%
Over a month
2,735 41%

Time from the first dose to the first sign, where both dates were reported (6,609 reports).

How the animals did

Recovered
1,937 22%
Recovered with lasting effects
184 2.1%
Still unwell when reported
3,349 37%
Died
444 5.0%
Euthanised
686 7.7%
Not known
2,340 26%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other corticosteroids for dogs