Prednisolone side effects in dogs

1,211 reports sent to the FDA between 1995 and 2026 involve Prednisolone in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 51% were marked serious, and where it was recorded, signs eased after stopping the medicine in 91% of cases.

1,211Reports
51%Marked serious
6.3%Only medicine involved
20%Recovered
17%Died or euthanised
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About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop worms
17 1.4%
Didn't stop fleas
15 1.2%
Didn't stop ticks
2 0.2%

How soon problems started

Same day
157 18%
1–2 days
104 12%
3–7 days
78 8.9%
1–4 weeks
180 20%
Over a month
360 41%

Time from the first dose to the first sign, where both dates were reported (879 reports).

How the animals did

Recovered
228 19%
Recovered with lasting effects
18 1.5%
Still unwell when reported
475 39%
Died
110 9.1%
Euthanised
94 7.8%
Not known
286 24%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other corticosteroids for dogs