Dexamethasone side effects in dogs

2,724 reports sent to the FDA between 1995 and 2026 involve Dexamethasone in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 69% were marked serious, and where it was recorded, signs eased after stopping the medicine in 50% of cases.

2,724Reports
69%Marked serious
1.4%Only medicine involved
21%Recovered
23%Died or euthanised
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About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
16 0.6%
Didn't stop worms
7 0.3%
Didn't stop ticks
3 0.1%
Didn't stop mites
1 0.0%

How soon problems started

Same day
1,069 45%
1–2 days
332 14%
3–7 days
229 9.6%
1–4 weeks
310 13%
Over a month
456 19%

Time from the first dose to the first sign, where both dates were reported (2,396 reports).

How the animals did

Recovered
565 21%
Recovered with lasting effects
18 0.7%
Still unwell when reported
1,112 41%
Died
345 13%
Euthanised
283 10%
Not known
401 15%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other corticosteroids for dogs