Diarrhea after Dexamethasone in dogs

The FDA has received 508 reports of diarrhea in dogs after Dexamethasone. That is 19% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

508Reports
77%Marked serious
22%Recovered
24%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
240 52%
1–2 days
73 16%
3–7 days
34 7.3%
1–4 weeks
41 8.9%
Over a month
75 16%

How the animals did

Recovered
110 22%
Recovered with lasting effects
3 0.6%
Still unwell when reported
223 44%
Died
63 12%
Euthanised
57 11%
Not known
52 10%

Problems reported at the same time

Age of the animals

Under 1 year
57
1–3 years
180
4–7 years
133
8–11 years
95
12+ years
39

About this medicine

Dexamethasone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Dexamethasone cause diarrhea in dogs?
508 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Dexamethasone in dogs · Medicines most reported with diarrhea