Diarrhea after Prednisone in dogs

The FDA has received 1,150 reports of diarrhea in dogs after Prednisone. That is 13% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,150Reports
61%Marked serious
24%Recovered
14%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
181 21%
1–2 days
126 14%
3–7 days
103 12%
1–4 weeks
170 19%
Over a month
297 34%

How the animals did

Recovered
256 22%
Recovered with lasting effects
19 1.7%
Still unwell when reported
443 39%
Died
50 4.3%
Euthanised
111 9.7%
Not known
271 24%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
280
4–7 years
363
8–11 years
303
12+ years
169

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause diarrhea in dogs?
1,150 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Prednisone in dogs · Medicines most reported with diarrhea