Lethargy after Prednisone in dogs

1,660 reports to the FDA describe lethargy in dogs given Prednisone. That is 19% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,660Reports
67%Marked serious
21%Recovered
23%Died or euthanised
11 daysTypical onset
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How soon it started

Same day
287 23%
1–2 days
154 12%
3–7 days
137 11%
1–4 weeks
269 21%
Over a month
425 33%

How the animals did

Recovered
307 18%
Recovered with lasting effects
39 2.3%
Still unwell when reported
609 37%
Died
139 8.4%
Euthanised
243 15%
Not known
323 19%

Problems reported at the same time

Age of the animals

Under 1 year
38
1–3 years
345
4–7 years
515
8–11 years
531
12+ years
217

About this medicine

Prednisone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisone cause lethargy in dogs?
1,660 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 11 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Prednisone in dogs · Medicines most reported with lethargy